ACRIXOLIMAB

UNII:	KHG83J8RMW
Formula:
Preferred Substance Name:	ACRIXOLIMAB
GSRS Full Record:	KHG83J8RMW i

2506324-29-2
ACRIXOLIMAB [INN]
IMMUNOGLOBULIN G4 (222-PROLINE), ANTI-(HUMAN PROGRAMMED CELL DEATH 1) (HUMAN MONOCLONAL YBL-006 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL YBL-006 .KAPPA.-CHAIN, DIMER
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD-1, PD1, CD279)), HOMO SAPIENS MONOCLONAL ANTIBODY; GAMMA4 HEAVY CHAIN HOMO SAPIENS (1-441) (VH (HOMO SAPIENS IGHV3-30*01 (95.8%)-(IGHD)- IGHJ5*01 (100%), CDR-IMGT (8.8.7) (26-33.51-58.97- 103)) (1-114)-HOMO SAPIENS IGHG4*01, G4V5 H P10 (CH1 (115-212), HINGE 1-12 S10>P (222) (213-224), CH2 (225-334), CH3 (335-439), CHS (440-441)) (115- 441)), (128-220')-DISULFIDE WITH KAPPA LIGHT CHAIN HOMO SAPIENS (1'-220') (V-KAPPA (HOMO SAPIENS IGKV2- 40*01 (94.1%)-IGKJ3*01 (91.7%) P120>Q (106), CDR-IMGT (12.3.9) (27-38.56-58.95-103)) (1'-113')- HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (159), V101 (197) (114'-220')); DIMER (220-220'':223-223'')- BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, CELL LINE CHO-DG44, GLYCOFORM ALFA

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UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ACRIXOLIMAB

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