LINOSERPATUREV

UNII:	KCT7UM8G55
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	LINOSERPATUREV
GSRS Full Record:	KCT7UM8G55 i

2933092-77-2
A recombinant oncolytic herpes simplex virus type 1 (HSV-1) F strain with the two γ134.5 genes plus the ICP6 gene partially deleted and a truncated γ134.5 gene reinserted into the ICP6 locus.
CAN-3110
DNA (recombinant tumor-selective replicating oncolytic human alphaherpesvirus 1 strain F vector CAN-3110 viral protein ICP34.5 gene deletion plus truncated ribonucleoside diphosphate reductase large subunit gene UL39-containing plus Rattus norvegicus nestin enhancer plus Mus musculus heat-shock protein HSP68 gene promoter plus human alphaherpesvirus 1 viral protein γICP34.5 gene reverse complementary-specifying)
LINOSERPATUREV [USAN]
Linoserpaturev
RQNestin34.5v.2 [WHO-DD]
linoserpaturev [INN]
rQNestin34.5v.2
recombinant oncolytic herpes simplex virus type 1 (HSV-1) F strain in which both copies of the viral gamma 1 34.5 gene (γ134.5, infected cell protein 34.5 [ICP34.5]) plus the ribonucleoside-diphosphate reductase large subunit UL39 (ICP6 gene) locus have been partially deleted/inactivated and in which a truncated copy of the γ134.5 gene has been re-inserted into the genome in the region of the UL39 (ICP6) deletion in reverse complementary orientation, under transcription control of a glioma-selective murine (Rattus norvegicus) nestin enhancer and a murine (Mus musculus) heat-shock protein 68 (HSP68) minimum gene promoter

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

LINOSERPATUREV

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