VERZISTOBART

UNII:	KAC8QY6TMN
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	VERZISTOBART
GSRS Full Record:	KAC8QY6TMN i

2649466-18-0
AGEN-2390
AGEN2390
INCAGN 02390 [WHO-DD]
INCAGN-02390
INCAGN02390
Immunoglobulin G1 [300-alanine,de-C-terminal-lysine], anti-(human T-cell immunoglobulin and mucin domain 3) (human monoclonal INCAGN02390 γ1-chain), disulfide with human monoclonal INCAGN02390 κ-chain, dimer
Immunoglobulin G1-kappa, anti-[Homo sapiens HAVCR2 (hepatitis A virus cellular receptor 2, T cell immunoglobulin and mucin domains family member 3, TIM3, TIM-3, TIMD3, CD366)], Homo sapiens monoclonal antibody (gamma1 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV3-23*04 (94.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, IGHG1v29 CH2 A84.4 (CH1 R120 (217) (121-218), hinge 1-15 (219-233), CH2 N84.4>A (300) (234-343), CH3 E12 (359), M14 (361) (344-448), CHS K2>del (449)) (121-449)], (223-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V- KAPPA (Homo sapiens IGKV3D-11*02 (96.7%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107')-Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (229-229'':232-232'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV lacking the glutamine synthetase (GS-KO) gene, non-glycosylated)
VERZISTOBART [USAN]
Verzistobart
verzistobart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

VERZISTOBART

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