OZISIRAN

UNII:	K699R35T33
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	OZISIRAN
GSRS Full Record:	K699R35T33 i

3061406-96-7
(2RS)-3-(1,23-bis[(2-acetamido-2-deoxy-β-D-galactopyranosyl) oxy]-14-{5-[(2-acetamido-2-deoxy-β-D-galactopyranosyl) oxy]pentanoyl}-5,19-dioxo-6,10,14,18-tetraazatricosan-10-yl)-2-hydroxy-3-oxopropyl hydrogen all-Pambo-2'-O-methyl-P-thiocytidylyl-(3'→5')-2'-O-methyl-Pthiocytidylyl-( 3'→5')-2'-O-methyluridylyl-(3'→5')-2'-Omethyluridylyl-( 3'→5')-2'-O-methylguanylyl-(3'→5')-2'-Omethyladenylyl-( 3'→5')-2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-Omethyluridylyl-( 3'→5')-2'-O-methyluridylyl-(3'→5')-2'-Omethylcytidylyl-( 3'→5')-2'-O-methyladenylyl-(3'→5')-2'-Omethyladenylyl-( 3'→5')-2'-O-methyl-3'-adenylate, duplex with all-P-ambo-2'-O-methyl-P-thiouridylyl-(5'→3')-2'-Omethyl-P-thiouridylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-Omethylguanylyl-( 5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-deoxy-2'-fluorouridylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-Omethylcytidylyl-( 5'→3')-2'-O-methylguanylyl-(5'→3')-2'-Omethyluridylyl-( 5'→3')-2'-O-methyladenylyl-(5'→3')-2'-Omethyluridylyl-( 5'→3')-2'-O-methylguanylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-Omethylguanylyl-( 5'→3')-2'-O-methyl-P-thiouridylyl-(5'→3')-2'-deoxy-2'-fluoro-P-thiouridylyl-(5'→3')-(5'E)-2'-O-methyl-5',C5'-didehydro-O5'-carba-5'-uridylic acid
Ozisiran
RNA, (Cm-sp-Cm-sp-Um-Um-Gm-Am-(2′-deoxy-2′-fluoro)G-(2′-deoxy-2′-fluoro)G-(2′-deoxy-2′-fluoro)C-Am-Um-Am-Cm-Um-Um-Cm-Am-Am-Am), 3′-[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl][3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]propyl][3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-2-hydroxy-3-oxopropyl hydrogen phosphate], complex with RNA ((5′,6′-dideoxy-6′-phosphono-β-D-ribo-hex-5-enofurano)Um-sp-(2′-deoxy-2′-fluoro)U-sp-Um-Gm-Am-(2′-deoxy-2′-fluoro)A-Gm-Um-Am-Um-Gm-Cm-Cm-(2′-deoxy-2′-fluoro)U-Cm-(2′-deoxy-2′-fluoro)A-Am-Gm-Gm-sp-Um-sp-Um) (1:1)
ozisiran [INN]

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OZISIRAN

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