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LORIGERLIMAB

UNII:JM802R57SA
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:LORIGERLIMAB
GSRS Full Record:
JM802R57SA
i

  • 2416595-46-3
  • AEX-1344
  • AEX1344
  • IMMUNOGLOBULIN G4 SCFV-H-CH2-CH3_SCFV, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD1, PD-1, CD279)) AND ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)), CHIMERIC, HOMO SAPIENS AND HUMANIZED MONOCLONAL ANTIBODY, TETRAVALENT, BISPECIFIC; SCFV-H-CH2-CH3, CHIMERIC AND HOMO SAPIENS, ANTI-PDCD1 AND ANTI-CTLA4 (1-499) (SCFV-V-KAPPA-VH (1-237) (V-KAPPA ANTI-PDCD1 MUSMUS/HOMSAP (MUS MUSCULUS IGKV3-2*01 (80.8%)-(IGHD)-IGKJ2*01 (91.7%) L124>V (108)/HOMO SAPIENS IGKV3D-11*02 (77.7%)-(IGHD)-IGKJ4*01 (100%), CDR-IMGT (10.3.9) (27-36.54-56.93-101)) (1-111)-8 MER TRIGLYCYL-SERYL-TETRAGLYCYL LINKER (112-119)-VH ANTI-CTLA4 (HOMO SAPIENS IGHV3-30*01 (93.9%)-(IGHD)-IGHJ4*01 (100%), CDR-IMGT (8.8.11) (145-152.170-177.216-226)) (120-237))-E-COIL LINKER (238-271) (6-MER DIGLYCYL-CYSTEINYL-TRIGLYCYL LINKER (238-243)-28-MER (GLUTAMYL-VALYL-DIALANYL-CYSTEINYL-GLUTAMYL-LYSYL)-TRIS(GLUTAMYL-VALYL-DIALANYL-LEUCYL-GLUTAMYL-LYSYL) E-COIL MOTIF (244-271))-(SCFC HOMO SAPIENS IGHG4*01 H-CH2-CH3, G4V5 H P10, G4V21 CH2 Y15.1, T16, E18 (HINGE 1-12 S10>P (281) (272-283), CH2 M15.1>Y (305), S16>T (307), T18>E (309) (284-393), CH3 (394-498), CHS K2>DEL (499)) (272-499)) (248''-246')-DISULFIDE WITH SCFV-V-KAPPA-VH, HOMO SAPIENS AND HUMANIZED, ANTI-CTLA4 AND ANTI-PDCD1 (1'-269') (V-KAPPA ANTI-CTLA4 (HOMO SAPIENS IGKV3-20*01 (99.0%)-IGKJ1*01 (100%), CDR-IMGT (7.3.9) (27-33.51-53.90-98)) (1'-108')-8 MER TRIGLYCYL-SERYL-TETRAGLYCYL LINKER (109'-116')-VH ANTI-PDCD1 (HOMO SAPIENS IGHV1-46*01 (81.6%)-(IGHD)-IGHJ4*01 (92.9%), CDR-IMGT (8.8.12) (142-149.167-174.213-224)) (117'-235'))-K-COIL LINKER (236'-269') (6-MER DIGLYCYL-CYSTEINYL-TRIGLYCYL LINKER (236'-241')-28-MER (LYSYL-VALYL-DIALANYL-CYSTEINYL-LYSYL-GLUTAMYL)-TRIS(LYSYL-VALYL-DIALANYL-LEUCYL-LYSYL-GLUTAMYL) K-COIL MOTIF (242'-269')); DIMER (279-279'':282-282'')-BISDISULFIDE, PRODUCED IN A CHINESE HAMSTER OVARY (CHO)-S CELL LINE, GLYCOFORM ALFA
  • IMMUNOGLOBULIN, ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1) (HUMAN-MUS MUSCULUS CLONE MG13.78 .KAPPA.-CHAIN V-J REGION) FUSION PROTEIN WITH PEPTIDE LINKER (GGGSGGGG) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4) (HUMAN CLONE 4B6 HEAVY CHAIN V-D-J REGION) FUSION PROTEIN WITH PEPTIDE LINKER (GGCGGG) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC E-COIL) FUSION PROTEIN WITH IMMUNOGLOBULIN G4 (10-PROLINE,34-TYROSINE,36-THREONINE,38-GLUTAMIC ACID,DE-229-LYSINE) (HUMAN .GAMMA.4-CHAIN C REGION C-TERMINAL FRAGMENT), DISULFIDE WITH IMMUNOGLOBULIN ANTI-(HUMAN CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4) (HUMAN CLONE 4B6 .KAPPA.-CHAIN V-J REGION) FUSION PROTEIN WITH LINKER PEPTIDE (GGGSGGGG) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1) (HUMAN-MUS MUSCULUS CLONE MG13.78 HEAVY CHAIN V-D-J REGION) FUSION PROTEIN WITH PEPTIDE LINKER (GGCGGG) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC K-COIL), DIMER
  • LORIGERLIMAB [USAN]
  • Lorigerlimab [WHO-DD]
  • MGD-019
  • MGD019
  • lorigerlimab [INN]




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