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ZICLUMERAN

UNII:JJ5AS2HL3G
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:ZICLUMERAN
GSRS Full Record:
JJ5AS2HL3G
i

  • 2305431-29-0
  • Messenger RNA (mRNA), 5' capped, encoding codon-optimised clustered regularly interspaced short palindromic repeats (CRISPR) associated protein 9 (Cas9), flanked by untranslated regions (UTR) with significant sequence homology to the Xenopus beta globin gene, and terminated with a polyadenylation (polyA) tail. A Kozak sequence precedes the open reading frame and the 5' cap is a synthetic anti-reverse cap analogue (ARCA); contains N1-methylpseudouridine instead of uridine (all-U>m1Ψ)
  • NTLA-2001 component mRNA000042
  • RNA (recombinant 5′-(m7Gm-(5′→5′)-ppp-G)-capped all uridine→N1-methylpseudouridine-substituted synthetic CRISPR-associated endodeoxyribonuclease CAS9 low codon A-optimized-specifying plus Xenopus laevis β-globin 5′-and 3′-untranslated flanking region-containing poly(A)-tailed messenger)
  • RNA (recombinant 5′-(m7Gm-(5′→5′)-ppp-G)-capped all uridine→N1-methylpseudouridinesubstituted synthetic CRISPR-associated endodeoxyribonuclease CAS9 low codon Aoptimized-specifying plus Xenopus laevis β-globin 5′-and 3′-untranslated flanking regioncontaining poly(A)-tailed messenger)
  • ZICLUMERAN [USAN]
  • ZICLUMERAN [USAN]
  • Ziclumeran
  • cas9 mRNA
  • cas9 mRNA (mRNA000042)
  • ziclumeran [INN]




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