ZARUTATUG

UNII:	JA8TYW9HZD
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ZARUTATUG
GSRS Full Record:	JA8TYW9HZD i

3038456-02-6
H-gamma1 heavy chain humanized (1-452) [VH (Homo sapiens IGHV1-69*02 (81.6%) -(IGHD) -IGHJ4*01 (86.7%) L123>T (117), V124>L (118), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (219) (123-220), hinge 1-15 (221-235), CH2 (236-345), CH3 D12 (361), L14 (363) (346-450), CHS (451-452)) (123-452)], (225-215')-disulfide with L-kappa light chain humanized (1'-215') [V-KAPPA (Homo sapiens IGKV1D-13*01 (84.2%) -IGKJ2*02 (100%), CDR-IMGT [7.3.9] (27'-33'.51'-53'.90'-98')) (1'-108') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (154'), V101 (192')) (109'-215')]; dimer (231-231'':234-234'')-bisdisulfide, produced in a cell line from Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, glycoform alfa
Immunoglobulin G1, anti-(human cadherin 17) (human-Mus musculus monoclonal TORL-3-600 γ1-chain), disulfide with human-Mus musculus monoclonal TORL-3-600 κ-chain, dimer
TORL-3-600 mAb
Zarutatug
immunoglobulin G1-kappa, anti-[Homo sapiens CDH17 (cadherin 17)], humanized monoclonal antibody (zarutatug)
zarutatug [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ZARUTATUG

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