NARLUMOSBART

UNII:	J38KT46AH8
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	NARLUMOSBART
GSRS Full Record:	J38KT46AH8 i

2646587-68-8
Immunoglobulin G4 [230-proline], anti-(human osteoclast differentiation factor) (human monoclonal JMT103 γ4-chain), disulfide with human monoclonal JMT103 κ-chain, dimer
Narlumosbart
Narlumosbart [WHO-DD]
gamma4 heavy chain Homo sapiens (1-449) [VH(Homo sapiens IGHV3-23*01 (98.0%)-(IGHD)-IGHJ5*02 (93.8%), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122)-Homo sapiens IGHG4*01, G4v5 hP10, nG4m(a) CH2 L92 (CH1(123-220), hinge 1-12, S10>P(230) (221-232), CH2 L92 (311) (233-342), CH3 (343-447), CHS (448-449)) (123-449)], (136-215')-disulfide with kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV3-20*01 (85.8%)-IGKJ1*01 (100%), CDR-IMGT [7.3.9] (27-33.51-53.90-98)) (1'-108') -Homo sapiens IGKC*01(100%), Km3 A45.1 (154), V101 (192) (109'-215')], dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-S, glycoform alfa
immunoglobulin G4-kappa, anti-[TNFSF11 (tumor necrosis factor (TNF) superfamily member 11, osteoclast differentiation factor, ODF, OPGL, RANKL, TRANCE, CD254)], Homo sapiens monoclonal antibody
narlumosbart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

NARLUMOSBART

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