LAFUVITUG

UNII:	IS3OH21U4J
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	LAFUVITUG
GSRS Full Record:	IS3OH21U4J i

2743342-91-6
3BNC-117
3BNC117
Immunoglobulin G1, anti-(human immunodeficiency virus 1 envelope glycoprotein gp120env CD4-binding site) (human monoclonal 3BNC117 γ1-chain), disulfide with human monoclonal 3BNC117 κ-chain, dimer
Lafuvitug
gamma1 heavy chain Homo sapiens (1-453) [VH (Homo sapiens IGHV1-2*02 (62.7%) -(IGHD) -IGHJ3*01 (85.7%), CDR-IMGT [8.8.12] (26-33.51-58.101-112), FR3 insertion D84.1, F84.2, D85.2, T85.1 (77-80))(1-123) -Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, CH3D12, L14 (CH1 K120 (220) (124-221), hinge 1-15 (222-236), CH2 (237-346), CH3 D12 (362), L14 (364) (347-451), CHS (452-453)) (124-453)],(226-206')-disulfide with kappa light chain Homo sapiens (1'-206') [V-KAPPA (Homo sapiens IGKV1-33*01 (72.8%) -IGKJ5*01 (41,6%)del(F118, G119, Q120) 92^93, E125>D (97), I126>L (98), CDR-IMGT[2.3.8] (27-28.46-48.85-92)) (1'-99') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (145), V101 (183) (100'-206')]; dimer (232-232'':235-235'')- bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHOK1SV, glycoform alfa
lafuvitug [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

LAFUVITUG

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