LATOZINEMAB

UNII:	IKT0XSS2XB
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	LATOZINEMAB
GSRS Full Record:	IKT0XSS2XB i

2376132-27-1
AL-001
AL001
Immunoglobulin G1 [239-alanine,240-alanine,336-serine], anti-(human sortilin-1) (human monoclonal AL001 γ1-chain), disulfide with human monoclonal AL001 κ-chain, dimer
Immunoglobulin G1-kappa, anti-[Homo sapiens SORT1 (sortilin 1, Gp95, NT3)], Homo sapiens monoclonal antibody; gamma1 heavy chain Homo sapiens (1-452) [VH (Homo sapiens IGHV4-38-2*01 (99.0%) -(IGHD) -IGHJ6*01 (100%)) CDR-IMGT [9.7.15] (26-34.52-58.97-111) (1-122) -Homo sapiens IGHG1*01 G1m17,1, G1v40 CH2 A1.3, A1.2, S116 (CH1 K120 (219) (123-220), hinge 1-15 (221-235), CH2 L1.3>A (239), L1.2>A (240), P116>S (336) (236-345), CH3 D12 (361), L14 (363) (346-450), CHS (451-452)) (123-452)], (225-219')-disulfide with kappa light chain Homo sapiens (1'-219') [V-KAPPA (Homo sapiens IGKV2-28*01 (93.0%) -IGKJ4*01 (100%)) CDR-IMGT [11.3.9] (27-37.55-57.94-102) (1'-112') -Homo sapiens IGKC*01 (100%) Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (231-231'':234-234'')-bisdisulfide, produced in a glutamine synthetase-Chinese hamster ovary (CHO) cell based expression system, GSKO CHOK1SV, glycoform alfa
LATOZINEMAB [USAN]
Latozinemab [WHO-DD]
latozinemab [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

LATOZINEMAB

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