RILIPRUBART

UNII:	I31869XDP8
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	RILIPRUBART
GSRS Full Record:	I31869XDP8 i

2756228-76-7
Anti-C1s Humanized IgG4 Monoclonal Antibody
BIVV-020
BIVV020
Immunoglobulin G4 [224-proline,234-glutamic acid,427-lysine,433-serine], anti-(human complement C1s) (human-Mus musculus monoclonal SAR445088 γ4-chain), disulfide with human-Mus musculus monoclonal SAR445088 κ-chain, dimer
RILIPRUBART [USAN]
Riliprubart
Riliprubart [WHO-DD]
SAR-445088
SAR445088
TNT-020
TNT020
immunoglobulin G4-kappa, anti-[Homo sapiens C1S (complement C1s)], monoclonal antibody; gamma4 heavy chain (1-446) [VH Musmus/Homsap (Mus musculus IGHV14-3*02 (82.7%) -(IGHD) -IGHJ2*01 (92.9%)/Homo sapiens IGHV1-46*02 (75.5%) -(IGHD) -IGHJ4*01 (92.9%) L123>T (114)), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10, G4v3 CH2 E1.2, G4v24 CH3 L107, S114 (CH1 (120-217), hinge 1-12 S10>P (227) (218-229), CH2 L1.2>E (234), L92 (308) (230-339), CH3 M107>L (427), N114>S (433) (340-444), CHS (445-446)) (120-446)], (133-218')-disulfide with kappa light chain (1'-218') [V-KAPPA Musmus/Homsap (Mus musculus IGKV3-4*01 (88.9%) -IGKJ1*01 (91.7%)/Homo sapiens IGKV4-1*01 (74.3%) -IGKJ4*01 (100%)), CDR-IMGT [10.3.9] (27-36.54-56.93-101)) (1'-111') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (157), V101 (195) (112'-218')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
riliprubart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

RILIPRUBART

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