VAROKIBART

UNII:	HO08KW5LSB
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	VAROKIBART
GSRS Full Record:	HO08KW5LSB i

2643349-04-4
Immunoglobulin G4 [225-proline,249-tyrosine,251-threonine,253-glutamic acid,de-444-lysine], anti-(human interleukin 5) (human clone 3A5.046 γ4-chain), disulfide with human clone 3A5.046 λ-chain, dimer
Immunoglobulin G4 [225-proline,249-tyrosine,251-threonine,253-glutamic acid,de-C-terminal-lysine], anti-(human interleukin 5) (human monoclonal TEV-53275 γ4-chain), disulfide with human monoclonal TEV-53275 λ-chain, dimer
TEV-53275
Varokibart
gamma4 heavy chain Homo sapiens (1-443) [VH (Homo sapiens IGHV4-31*02 (99%) -(IGHD) -IGHJ5*01 (93.8%)) [10.7.9](26-35.53-59.98-106) (1-117) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10, G4v21 CH2 Y15.1, T16, E18 (CH1 (118-215), hinge 1-12 S10>P (225) (216-227), CH2 L92 (312), M>Y15.1 (249), S>T16 (251), T>E18 (253) (228-337), CH3 (338-442), CHS K2>del (443)) (118-443)], (131-213')-disulfide with lambda light chain Homo sapiens (1'-214') [V-LAMBDA (Homo sapiens IGLV1-21*02 (94.8%) -IGLJ2*01 (100%)) [6.3.11] (26-31.49-51.88-98) (1'-108')-Homo sapiens IGLC2*01(100%) (109'-214')]; dimer(223-223'':226-226'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV, glycoform alfa
immunoglobulin G4-lambda, anti-[Homo sapiens IL5 (interleukin 5, IL-5)], Homo sapiens monoclonal antibody
varokibart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

VAROKIBART

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