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AMULIRAFUSP ALFA

UNII:HFR7WU5YK7
Formula:
Preferred Substance Name:AMULIRAFUSP ALFA
GSRS Full Record:
HFR7WU5YK7
i

  • 2850355-94-9
  • 1-133-SIGNAL REGULATORY PROTEIN .ALPHA. (80-ALANINE) (HUMAN ISOFORM 4 VARIANT) FUSION PROTEIN WITH PEPTIDE LINKER ((GGGGS)2) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (445-ALANINE,530-ALANINE,531-ALANINE) ANTI-(HUMAN CD20 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IMM0306 .GAMMA.1-CHAIN) DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL IMM0306 .KAPPA.-CHAIN, DIMER
  • AMULIRAFUSP ALFA [INN]
  • HUMAN SIGNAL REGULATORY PROTEIN ALPHA (SIRP ALPHA VARIANT V2 EXTRACELLULAR D1 DOMAIN, SIRP ALPHA V2D1) FRAGMENT 31-163, COMPRISING THE FIRST TWO EXTRACELLULAR LOOPS OF THE D1 DOMAIN, (N110>A80)-VARIANT, ANTI-(HUMAN CD47, INTEGRIN ASSOCIATED PROTEIN (IAP)) (1-133 IN THE CURRENT SEQUENCE) FUSED VIA A (G4S) 2 PEPTIDE LINKER (134-143) TO GAMMA 1 HEAVY CHAIN (144-594) (VH (MUS MUSCULUS IGHV1-12*01 -(IGHD) -IGHJ1*01, CDR-KABAT (5.17.12)(174-178.193-209.242-253)) (144-264) -HOMO SAPIENS IGHG1*03(CH1 (265-362), HINGE (363-377), CH2 S445>A, E480>A, K 481>A (378-487), CH3 (488-592), CHS (593-594)) (265-594)), (367-213')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-213') (V-KAPPA (MUS MUSCULUS IGKV4-72*01 -IGKJ1*01, CDR-KABAT (10.7.9) (24'-33'.49'-55'.88'-96')) (1'-106') -HOMO SAPIENS IGKC*01 (107'-213')); DIMER (373-373'':376-376'')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, CELL LINE CHO-K1, GLYCOFORM ALFA
  • HUMAN SIGNAL REGULATORY PROTEIN ALPHA (SIRP.ALPHA.) FRAGMENT, ANTI-(HUMAN CD47, INTEGRIN ASSOCIATED PROTEIN (IAP)), FUSED VIA A (G4>S)2PEPTIDE LINKER TO THE N-TERMINUS OF BOTH HEAVY CHAINS OF A CHIMERIC IMMUNOGLOBULIN G1-KAPPA ANTI-(HUMAN B-LYMPHOCYTE ANTIGEN CD20), GLYCOFORM ALFA
  • IMM 0306 [WHO-DD]
  • IMM0306
  • IMM-0306
  • IMM0306 (BISPECIFIC ANTIBODY-TRAP SELECTIVELY TARGETING CD47 AND CD20)




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