LUSVERTIKIMAB

UNII:	H1V41MWX63
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	LUSVERTIKIMAB
GSRS Full Record:	H1V41MWX63 i

2375835-91-7
Immunoglobulin G4 [100-leucine,230-proline,447-proline], anti-(human interleukin-7 receptor subunit α) (human-Rattus norvegicus monoclonal OSE-127 γ4-chain), disulfide with [31-glutamine,53-threonine] human-Rattus norvegicus monoclonal OSE-127 κ-chain, dimer
Immunoglobulin G4-kappa, anti-[Homo sapiens IL7R (interleukin 7 receptor, CD127, IL7RA)], humanized monoclonal antibody; gamma4 heavy chain humanized (1-449) [VH (Homo sapiens IGHV3-11*01 (90.8%) -(IGHD) -IGHJ4*01 (100%)) CDR-IMGT [8.8.15] (26-33.51-58.97-111) (1-122)-Homo sapiens IGHG4*01 (100%), G4v5 h P10 (CH1 (123-220), hinge 1-12 S10>P (230) (221-232), CH2 (233-342), CH3 (343-447), CHS (448-449)) (123-449)], (136-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-NL1*01 (86.3%) -IGKJ4*01 (91.7%)) CDR-IMGT [6.3.9] (27-32.50- 52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (228-228'':231-231'')- bisdisulfide, produced in a Chinese hamster ovary (CHO)-K1 cell line, glycoform alfa
LUSVERTIKIMAB [USAN]
Lusvertikimab
Lusvertikimab [WHO-DD]
OSE-127
lusvertikimab [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

LUSVERTIKIMAB

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