OSEMITAMAB

UNII:	H14V1A2F4D
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	OSEMITAMAB
GSRS Full Record:	H14V1A2F4D i

2460539-61-9
Immunoglobulin G1, anti-(human claudin 18.2) (human-Mus musculus monoclonal TST001 γ1-chain), disulfide with human-Mus musculus monoclonal TST001 κ-chain, dimer
Immunoglobulin G1-kappa, anti-[Homo sapiens CLDN18 (SFTPJ, surfactant associated protein J) isoform 2, extracellular domain 1 (EC1)], humanized monoclonal antibody; gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV1-46*01 (87.8%) -(IGHD) -IGHJ4*01 (92.9%) L123>T (113), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (215) (119-216), hinge 1-15 (217-231), CH2 (232-341), CH3 D12 (357), L14 (359) (342-446), CHS (447-448)) (119-448)], (221-220')-disulfide with kappa light chain humanized (1'-220') [VKAPPA (Homo sapiens IGKV4-1*01 (91.1%) - IGKJ4*01 (100%), CDR-IMGT [12.3.9] (27-38.56-58.95-103)) (1'-113') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (159), V101 (197) (114'-220')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1 lacking the glutamine synthetase (GS-KO) gene, glycoform alfa
MSB-018
OSEMITAMAB [USAN]
Osemitamab
TST 001 [WHO-DD]
TST-001
TST001
osemitamab [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

OSEMITAMAB

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