DEBAMESTROCEL

UNII:	GPC34QP6X6
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	DEBAMESTROCEL
GSRS Full Record:	GPC34QP6X6 i

AUTOLOGOUS MESENCHYMAL STROMAL CELLS (MSC) SECRETING NEUROTROPHIC FACTORS (NTF)
AUTOLOGOUS MESENCHYMAL STROMAL CELLS SECRETING NEUROTROPHIC FACTORS
AUTOLOGOUS MSC-NTF
DEBAMESTROCEL [USAN]
Debamestrocel
NurOwn
The MSC-NTF cells are Mesenchymal Stem Cells (MSC) secreting Neurotrophic factors. The autologous MSC are isolated from the mononuclear fraction of the patient’s own Bone Marrow (BM), propagated ex-vivo in a xeno-free growth medium and induced to differentiate into MSCs secreting high levels of Neurotrophic factors (NTF) in a proprietary defined differentiation medium. Once propagated to a large number of cells, MSC are harvested and cryopreserved for providing fresh MSC-NTF cells for each repeated dosing cycle. In advance of each treatment cycle MSC are thawed propagated and induced to differentiate into MSC-NTF cells which are administered to the patient
debamestrocel [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

DEBAMESTROCEL

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