SURABGENE LOMPARVOVEC

UNII:	GJI4EV4B3C
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	SURABGENE LOMPARVOVEC
GSRS Full Record:	GJI4EV4B3C i

2374935-18-7
A recombinant, non-replicating adeno-associated virus serotype 8 (rAAV8) vector encoding an anti-vascular endothelial growth factor (VEGF) antibody fragment (Fab).
ABBV-314
DNA (recombinant replication-defective adeno-associated virus 8 vector RGX-314 cytomegalovirus immediate-early enhancer element plus chicken β-actin gene promoter plus chicken β-actin gene intron plus human-Mus musculus anti-(human vascular endothelial growth factor) immunoglobulin G1 Fab fragment γ1-chain fusion protein with synthetic F2A peptide linker fusion protein with human-Mus musculus immunoglobulin κ-chain codon-optimized gene plus rabbit β-globin polyadenylation signal plus adeno-associated virus 8 inverted terminal repeat flanks)
RGX-314
SURABGENE LOMPARVOVEC [USAN]
Surabgene Lomparvovec
Surabgene lomparvovec [WHO-DD]
recombinant, non-replicating adeno-associated virus serotype 8 (rAAV8) vector encoding a soluble humanised anti-vascular endothelial growth factor (VEGF) antibody fragment (Fab) under control of a hybrid cytomegalovirus (CMV) immediate-early enhancer/chicken β-actin promoter, enhanced by a chicken β-actin intron and terminated by a rabbit β-globin polyadenylation signal. The heavy and light chains of the Fab are separated by a self-cleaving furin /F2A linker and the transgene is flanked by adeno-associated virus 2 (AAV2) inverted terminal repeats (ITRs)
surabgene lomparvovec [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

SURABGENE LOMPARVOVEC

Synonyms and Mappings

Resources