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DATOPOTAMAB DERUXTECAN

UNII:GD2OWY1DTK
Formula:
Preferred Substance Name:DATOPOTAMAB DERUXTECAN

  • 2238831-60-0
  • ANTI-TROP2/DXD ANTIBODY-DRUG CONJUGATE DS-1062A
  • DATO-DXD
  • DATOPOTAMAB DERUXTECAN [INN]
  • DATOPOTAMAB DERUXTECAN [USAN]
  • DATOPOTAMAB DERUXTECAN [WHO-DD]
  • DATOPOTAMAB DERUXTECAN-DLNK
  • DATROWAY
  • DS1062
  • DS-1062
  • DS-1062A
  • IMMUNOGLOBULIN G1, ANTI-(HUMAN TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER 2) (HUMAN-MUS MUSCULUS MONOCLONAL MAAP-9001 .GAMMA.1-CHAIN), COMPD. WITH HUMAN-MUS MUSCULUS MONOCLONAL MAAP-9001 .KAPPA.-CHAIN, DIMER, THIOETHER WITH N-(6-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1-OXOHEXYL)GLYCYLGLYCYL-L-PHENYLALANYL-N-((2-(((1S,9S)-9-ETHYL-5-FLUORO-2,3,9,10,13,15-HEXAHYDRO-9-HYDROXY-4-METHYL-10,13-DIOXO-1H,12H-BENZO(DE)PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLIN-1-YL)AMINO)-2-OXOETHOXY)METHYL)GLYCINAMIDE
  • IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS TACSTD2 (TUMORASSOCIATED CALCIUM SIGNAL TRANSDUCER 2, MEMBRANE COMPONENT CHROMOSOME 1 SURFACE MARKER 1, M1S1, GASTROINTESTINAL TUMORASSOCIATED ANTIGEN GA7331, PANCREATIC CARCINOMA MARKER PROTEIN GA733-1, EPITHELIAL GLYCOPROTEIN-1, EGP-1, TROPHOBLAST ANTIGEN-2, CELL SURFACE GLYCOPROTEIN TROP-2, TROP2)), HUMANIZED MONOCLONAL ANTIBODY CONJUGATED TO DERUXTECAN, COMPRISING A LINKER AND A CAMPTOTHECIN DERIVATIVEGAMMA1 HEAVY CHAIN HUMANIZED (1-451) (VH (HOMO SAPIENS IGHV1-3*01(79.6%)-(IGHD)-IGHJ4*01 (93.3%)) CDR-IMGT (8.8.14) (26-33.51-58.97-110) (1-121)-HOMO SAPIENS IGHG1*03 (100%) G1M3, NG1M1 (CH1 R120 (218) (122-219), HINGE 1-15 (220-234), CH2 (235-344), CH3 E12 (360), M14 (362) (345-449), CHS (450-451)) (118-451)), (224-214')-DISULFIDE WITH KAPPA LIGHT CHAIN HUMANIZED (1'-214') (V-KAPPA (HOMO SAPIENS IGKV1-39*01 (84.2%)-IGKJ2*01 (100%)) CDR-IMGT (6.3.9) (27-32.50-52.89-97) (1'-107')-HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (153), V101 (191) (108'-214'))DIMER (230-230'':233-233'')-BISDISULFIDEPRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM ALFA, CONJUGATED, ON AN AVERAGE OF 4 CYSTEINYL, TO DERUXTECAN, COMPRISING A LINKER AND A CAMPTOTHECIN DERIVATIVE




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