ROCATINLIMAB

UNII:	G770V925KP
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ROCATINLIMAB
GSRS Full Record:	G770V925KP i

2431972-52-8
AMG-451
AMG451
Immunoglobulin G1, anti-(human CD134 antigen) (human monoclonal KHK4083 γ1-chain), disulfide with human monoclonal KHK4083 κ-chain, dimer
KHK-4083
KHK4083
ROCATINLIMAB [USAN]
Rocatinlimab
Rocatinlimab [WHO-DD]
immunoglobulin G1-kappa, anti-[Homo sapiens TNFRSF4 (tumor necrosis factor receptor (TNFR) superfamily member 4, OX40, CD134)], Homo sapiens monoclonal antibody; gamma1 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV2-5*02 (94.0%) -(IGHD) - IGHJ1*01 (100%), CDR-IMGT [10.7.9] (26-35.53- 59.98-106)) (1-117) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (214) (118-215), hinge 1-15 (216-230), CH2 (231-340), CH3 D12 (356), L14 (358) (341-445), CHS (446-447)) (118-447)], (220-214')- disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV3-20*01 (98.9%) - IGKJ4*01 (100%), CDR-IMGT [7.3.8] (27-33.51-53.90- 97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (226- 226'':229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
rocatinlimab [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ROCATINLIMAB

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