CILTISTOTUG

UNII:	G2CB897733
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	CILTISTOTUG
GSRS Full Record:	G2CB897733 i

3014361-59-9
CILTISTOTUG [USAN]
Ciltistotug
H-gamma2 heavy chain (1-441) [VH Musmus/Homsap (Mus musculus IGHV1-47-14*01 (84.7%) -(IGHD) -IGHJ2*01 (100%)/Homo sapiens IGHV1-2*02 (79.6%) -(IGHD) -IGHJ6*01 (90.9%) V124>L (111), CDR-IMGT [8.8.8] (26-33.51-58.97-104)) (1-115) -Homo sapiens IGHG2*01 G2m.. (100%) CH2 V45.1 (CH1 (116-213), hinge 1-12 (214-225), CH2 V45.1 (276) (226-334), CH3 (335-439), CHS (440-441)) (116-441)], (129-219')-disulfide with L-kappa light chain (1'-219') [V-KAPPA Musmus/Homsap (Mus musculus IGKV1-110*01 (88.0%) -IGKJ1*01 (91.7%) L124>V (109')/Homo sapiens IGKV2-30*02 (88.0%) -IGKJ4*01 (100%), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (158'), V101 (196')) (113'-219')]; dimer (217-217'':218-218'':221-221'':224-224'')-tetrakisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Immunoglobulin G2, anti-(human/Macaca mulatta CD40 antigen) (human-Mus musculus monoclonal YH003 γ2-chain), disulfide with human-Mus musculus monoclonal YH003 κ-chain, dime
YH 003 [WHO-DD]
YH-003
YH-003 (HUMANIZED AGONISTIC ANTI-CD40 IGG2 MONOCLONAL ANTIBODY)
YH003
ciltistotug [INN]
immunoglobulin G2-kappa, anti-[Homo sapiens CD40 (TNFRSF5, tumor necrosis factor receptor (TNFR) superfamily member 5, p50)], monoclonal antibody

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

CILTISTOTUG

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