GEPTANOLIMAB

UNII:	FME52R2SGN
Formula:
Preferred Substance Name:	GEPTANOLIMAB
GSRS Full Record:	FME52R2SGN i

2348469-43-0
APL-501
CBT-501
GB226
GB-226
GENOLIMZUMAB
GEPTANOLIMAB [INN]
GEPTANOLIMAB [WHO-DD]
HUMANIZED IGG4 ANTIBODY DIRECTED AGAINST THE NEGATIVE IMMUNOREGULATORY HUMAN CELL SURFACE RECEPTOR PROGRAMMED CELL DEATH 1 (PD-1/PDCD1/PD1) WITH LOW ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY AND COMPLEMENT-DEPENDENT CYTOTOXICITY
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD-1, PD1, CD279)), MONOCLONAL ANTIBODYGAMMA4 HEAVY CHAIN (1-440) (VH (HOMO SAPIENSIGHV7-4-1*02 (85.7%)-(IGHD)-IGHJ4*01 (100%)) CDR-IMGT (8.8.7) (26-33.51-58.97-103) (1-114)-HOMO SAPIENS IGHG4*01, G4V5 H P10 (CH1 (115-212), HINGE 1-12 S10>P (222) (213-224), CH2 (225-334), CH3 (335-439), CHS K>DEL (440) (115-440)), (28-217')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-217') (V-KAPPA (MUS MUSCULUS IGKV3-5*01 (89.9%)-IGKJ1*01 (90.9%)/HOMO SAPIENS IGKV3D-11*02 (64.9%)-IGKJ2*01 (100%)) CDR-IMGT (10.3.8) (27-36.54-56.93-100) (1'-110')-HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (156), V101 (194) (111'-217'))DIMER (220-220'':223-223'')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO)-S CELL LINE, GLYCOFORM ALFA
MMUNOGLOBULIN G4 (232-PROLINE,DE-451-LYSINE), ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1) (HUMAN-MUS MUSCULUS MONOCLONAL GB226 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL GB226 .KAPPA.-CHAIN, DIMER

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

GEPTANOLIMAB

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