SIMLUKAFUSP ALFA

UNII:	FL08SGO9XA
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	SIMLUKAFUSP ALFA
GSRS Full Record:	FL08SGO9XA i

1776942-10-9
ANTI-FAP/INTERLEUKIN-2 FUSION PROTEIN RO6874281
FAP-IL-2V
FAP-IL2V
FAP-IL2V FP RO6874281
IMMUNOGLOBULIN G1, ANTI-(HUMAN SEPRASE) (HUMAN MONOCLONAL FAP-IL-2V HEAVY CHAIN) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC LINKER) FUSION PROTEIN WITH INTERLEUKIN 2 (HUMAN MUTANT QM IL-2), DISULFIDE WITH HUMAN MONOCLONAL FAP-IL-2V LIGHT CHAIN, DIMER WITH IMMUNOGLOBULIN G1, ANTI-(HUMAN SEPRASE) (HUMAN MONOCLONAL FAP-IL-2V HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL FAP-IL-2V LIGHT CHAIN
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS PROLYL ENDOPEPTIDASE FAP (FIBROBLAST ACTIVATION PROTEIN ALPHASURFACE-EXPRESSED PROTEASESEPRASEEC=3.4.21.26)).OMEGA. MONO-LINKED TO MODIFIED (HOMO SAPIENS INTERLEUKIN-2 (T-CELL GROWTH FACTOR, IL-2, ALDESLEUKIN))FUSION PROTEIN: .GAMMA.1 HEAVY CHAIN (1-446) (HOMO SAPIENS VH (IGHV3-23*01 (98%) (IGHD)-IGHJ4*01 (93%)) (8.8.10) (1-117)-HOMO SAPIENS IGHG1*01 (CH2(L4>A(234),L5>A(235),P99>G(329)), CH3(S14>C(354),T26>W(366),K107>DEL(447))) (118-446)) FUSION PROTEIN WITH TRIS(TETRAGLYCYLSERYL) (LINKER 447-461) AND WITH-HOMO SAPIENS INTERLEUKIN-2 (T3>A(464),F42>A(503),Y45>A(506),L72>G(533),C125>A(586)) (462-594) (220-215')-DISULFIDE WITH .KAPPA. LIGHT CHAIN (1'-215') (HOMO SAPIENS V-KAPPA (IGKV3-20*01 (95%) IGKJ1*01)(7.3.9) (1'-108')-HOMO SAPIENS IGKC*01 (109'-215')), (226-226'':229-229'':354-349'')-TRISDISULFIDE WITH .GAMMA.1 HEAVY CHAIN (1''-447'')(HOMO SAPIENS VH (IGHV3-23*01 (98%) (IGHD)-IGHJ4*01 (93%)) (8.8.10) (1''-117'')-HOMO SAPIENS IGHG1*01 (CH2(L4>A(234''),L5>A(235''),P99>G(329'')), CH3(Y9>C(349''),T26>S(366''),L28>A(368''),Y67>V(407''))) (118''-447'')) (220''-215''')-DISULFIDE WITH .KAPPA. LIGHT CHAIN (1'''-215''') (HOMO SAPIENS V-KAPPA (IGKV3-20*01 (95%) IGKJ1*01)(7.3.9) (1'''-108''')-HOMO SAPIENS IGKC*01 (109'''-215'''))
RG-7461
RG7461
RO-6874281
RO6874281
SIMLUKAFUSP ALFA [USAN]
Simlukafusp alfa [WHO-DD]
simlukafusp alfa [INN]

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UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

SIMLUKAFUSP ALFA

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