ABDAKIBART

UNII:	FJZ68XPT4U
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ABDAKIBART
GSRS Full Record:	FJZ68XPT4U i

3034641-53-4
ABDAKIBART [USAN]
AVTX-009
AVTX009
Abdakibart
FL101
H-gamma4 heavy chain humanized (1-447) [VH (Homo sapiens IGHV1-69*08 (85.7%) -(IGHD) -IGHJ2*01 (92.9%) R120>Q (112), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, 12-G4v5 h P10 (CH1 (121-218), hinge 1-12 S10>P (228) (219-230), CH2 L92 (309) (231-340), CH3 (341-445), CHS (446-447)) (121-447)], (134-214')-disulfide with L-kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-16*01 (82.1%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (226-226'':229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Immunoglobulin G4 [228-proline], anti-(human interleukin 1β) (human-Mus musculus monoclonal AVTX-009 γ4-chain), disulfide with human-Mus musculus monoclonal AVTX-009 κ-chain, dimer
Immunoglobulin G4-kappa, anti-[Homo sapiens IL1B (interleukin 1 beta, IL-1B, 1L1F2)], humanized monoclonal antibody
LY-2189102
LY2189102
abdakibart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ABDAKIBART

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