TIXESTOBART

UNII:	F6V3QF5HAK
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	TIXESTOBART
GSRS Full Record:	F6V3QF5HAK i

2733575-82-9
GEN-1053
GEN1053
Immunoglobulin G1 [102-serine,328-arginine,344-arginine,de-C-terminal-lysine], anti-(human CD27 antigen) (human monoclonal IgG1-7730-143-C102S-RR γ1-chain), disulfide with human monoclonal IgG1-7730-143-C102S-RR λ-chain, dimer
Tixestobart
immunoglobulin G1-lambda2, anti-[Homo sapiens CD27 (TNFRSF7, tumor necrosis factor receptor (TNFR) superfamily member 7)], Homo sapiens monoclonal antibody (H-gamma1 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV7-4-1*02 (91.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, 6-G1v4-2 CH2 R114, 10-G1v98 CH3 R1 (CH1 R120 (213) (117-214), hinge 1-15 (215-229), CH2 P114>R (328) (230-339), CH3 E1>R (344), E12 (355), M14 (357) (340-444), CHS K2>del (445)) (117-445)], (219-215')-disulfide with L-lambda2 light chain Homo sapiens (1'-216') [V-LAMBDA (Homo sapiens IGLV2-14*03 (94.7%) -IGLJ3*02 (100%), CDRIMGT [9.3.10] (26'-34'.52'-54'.91'-100')) (1'-110') -Homo sapiens IGLC2*01 (100%) (C-LAMBDA2) (111'-216')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa)
tixestobart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

TIXESTOBART

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