GIMVEKIBART

UNII:	EG4YAS2FCR
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	GIMVEKIBART
GSRS Full Record:	EG4YAS2FCR i

3037526-90-9
Gimvekibart
H-gamma4 heavy chain humanized (1-446) [VH (Homo sapiens IGHV3-74*01 (91.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, 12-G4v5 h P10 (CH1 (120-217), hinge 1-12 S10>P (227) (218-229), CH2 L92 (308) (230-339), CH3 (340-444), CHS (445-446)) (121-446)], (133-215')-disulfide with L-kappa light chain humanized (1'-215') [V-KAPPA (Homo sapiens IGKV1-39*01 (83.2%) -IGKJ1*01 (100%), CDR-IMGT [6.3.10] (27'-32'.50'-52'.89'-98')) (1'-108') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (154'), V101 (192')) (109'-215')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-S, glycoform alfa
Immunoglobulin G4 [227-proline], anti-(human interleukin 4 receptor subunit α) (human-Mus musculus monoclonal RAB-S05 γ4-chain), disulfide with human-Mus musculus monoclonal RAB-S05 κ-chain, dimer
gimvekibart [INN]
immunoglobulin G4-kappa, anti-[Homo sapiens IL4R (interleukin 4 receptor, IL4RA, IL-4RA, interleukin 13 receptor, CD124)], humanized monoclonal antibody (gimvekibart)

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

GIMVEKIBART

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