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ETIVELCABTAGENE ERIGEDLEUCEL

UNII:E4X5PXM3XS
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:ETIVELCABTAGENE ERIGEDLEUCEL
GSRS Full Record:

  • ETIVELCABTAGENE ERIGEDLEUCEL [USAN]
  • Etivelcabtagene erigedleucel
  • UCART20x22
  • UCART20x22 is defined as allogeneic, non-alloreactive T-cells, transduced with a self-inactivating (SIN) recombinant lentiviral vector to express two Chimeric Antigen Receptor (CAR) constructs, each of them directed against cluster of differentiation (CD)20 or CD22, and genetically edited with TALEN® (Transcription Activator Like Effector Nucleases) to disrupt the CD52 and the T cell receptor alpha constant (TRAC) genes



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