FALBIKITUG

UNII:	E4JL3K3CI6
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	FALBIKITUG
GSRS Full Record:	E4JL3K3CI6 i

2740565-02-8
AZD-0171
AZD0171
FALBIKITUG [USAN]
Falbikitug
Falbikitug [WHO-DD]
Immunoglobulin G1, anti-(human leukemia inhibitory factor) (human-Wistar rat monoclonal AZD0171 γ1-chain), disulfide with human-Wistar monoclonal AZD0171 κ-chain, dimer
Immunoglobulin G1-kappa, anti-[Homo sapiens LIF (LIF interleukin 6 family cytokine, leukemia inhibitory factor)], humanized monoclonal antibody
MSC-1
falbikitug [INN]
gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV3-15*07 (86.9%)--(IGHD) -IGHJ1*01(90.9%), CDR-IMGT [8.10.9] (26-33.51-60.99-107))(1-118) -Homo sapiens IGHG1*01 (100%), G1m17,1 CH1K120, CH3 D12, L14 (CH1 K120 (215) (119-216),hinge 1-15 (217-231), CH2 (232-341), CH3 D12 (357), L14 (359) (342-446), CHS (447-448)) (119-448)], (221-220')-disulfide with kappa light chain humanized (1'-220') [V-KAPPA (Homo sapiens IGKV2-24*01 (90.0%)-IGKJ2*01 (100%), CDR-IMGT [11.3.10] (27-37.55-57.94-103)) (1'-113') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (159), V101 (197) (114'-220')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, glycoform alfa

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

FALBIKITUG

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