ZOLACABTAGENE AUTOLEUCEL

UNII:	DU963TX85S
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ZOLACABTAGENE AUTOLEUCEL
GSRS Full Record:	DU963TX85S i

BMS-986353
BMS-986353 is an investigational CD19-targeted CAR T-cell product. The CD19-specific CAR consists of a single-chain variable fragment (scFv) binding domain derived from a CD19-specific monoclonal antibody (mAb; FMC63), an IgG-derived hinge region, a CD28 transmembrane domain, and the CD137 (41BB) and CD3ζ chain signaling domains. The third-generation SIN lentiviral vector, which encodes the CAR domains described above, also encodes a truncated human epidermal growth factor receptor (EGFRt) that is expressed separately from the CD19 CAR on the T cell surface
CC 97540 [WHO-DD]
CC-97540
ZOLACABTAGENE AUTOLEUCEL [USAN]
Zolacabtagene Autoleucel

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ZOLACABTAGENE AUTOLEUCEL

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