GIVILMERAN

UNII:	DQ7W4DRD5W
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	GIVILMERAN
GSRS Full Record:	DQ7W4DRD5W i

2924731-69-9
CX-035784
Givilmeran
RNA (recombinant 5′-(m7G-(5′→5′)-ppp-Gm)-capped all uridine→N1-methylpseudouridine-substituted 5′-untranslated region plus human methylmalonyl-coenzyme A mutase plus 3′-untranslated region-containing microRNA-142 binding sites plus poly(A)-tailed messenger CX-035784), inner salt
givilmeran [INN]
messenger RNA (mRNA), 5' capped, encoding codon-optimised human methylmalonyl-coenzyme A mutase (MMUT, MUT, MCM) flanked by 5' and 3' untranslated regions (UTRs) followed by a 3' polyadenylation (polyA) tail and concluded by a 5-nucleotide XbaI scar. The 3' UTR contains three microRNA-142 (miR-142) binding sites. Contains N1-methylpseudouridine instead of uridine (all-U>m1Ψ)

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UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

GIVILMERAN

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