UMIKIBART

UNII:	DET5J756VL
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	UMIKIBART
GSRS Full Record:	DET5J756VL i

2851478-58-3
H-gamma4 heavy chain humanized (1-443) [VH (Homo sapiens IGHV3-23*04 (89.8%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10, G4v3 CH2 E1.2 (CH1 (117-214), hinge 1-12 S10>P (224) (215-226), CH2 L92 (305), L1.2>E (231) (227-336), CH3 (337-441), CHS (442-443)) (117-443)], (130-215')-disulfide with Lkappa light chain humanized (1'-215') [V-KAPPA (Homo sapiens IGKV1-13*02 (94.3%) -IGKJ1*01 (100%), CDRIMGT [6.3.10] (27'-32'.50'-52'.89'-98')) (1'-108') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (154'), V101 (192') (109'-115')];dimer (222-222'':225-225'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa
Immunoglobulin G4 [224-proline], anti-(human hepatocyte growth factor) (human-Oryctolagus cuniculus monoclonal YYB101 γ4-chain), disulfide with human-Oryctolagus cuniculus monoclonal YYB101 κ-chain, dimer
Umikibart
YYB-101
YYB101
immunoglobulin G4-kappa, anti-[Homo sapiens HGF (hepatocyte growth factor, scatter factor, SF, hepatopoeitin A)], humanized monoclonal antibody
umikibart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

UMIKIBART

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