EPCORITAMAB

UNII:	D6OMY2L0WA
Formula:
Preferred Substance Name:	EPCORITAMAB

2134641-34-0
EPCORITAMAB [INN]
EPCORITAMAB [USAN]
EPCORITAMAB [WHO-DD]
EPCORITAMAB-BYSP
EPKINLY
GEN-3013
IMMUNOGLOBULIN G1 (234-PHENYLALANINE, 235-GLUTAMIC ACID, 265-ALANINE, 405-LEUCINE), ANTI-(HUMAN CD3 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IGG1-HUCACAO-FEAL .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL IGG1-HUCACAO-FEAL .LAMBDA.-CHAIN, (234->231'),(237->234')-BIS(DISULFIDE) WITH IMMUNOGLOBULIN G1 (234-PHENYLALANINE, 235-GLUTAMIC ACID, 265-ALANINE, 409-ARGININE) ANTI-(HUMAN CD20 ANTIGEN) (HUMAN MONOCLONAL IGG1-7D8-FEAR .GAMMA.1-CHAIN) DISULFIDE WITH HUMAN MONOCLONAL IGG1-7D8-FEAR .KAPPA.-CHAIN
IMMUNOGLOBULIN G1-LAMBDA/KAPPA, ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON)) AND ANTI-(HOMO SAPIENS MS4A1 (MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 1, CD20)), MONOCLONAL BISPECIFIC ANTIBODY; GAMMA1 HEAVY CHAIN CHIMERIC ANTI-CD3E (1-454) (VH (MUS MUSCULUS IGHV10-1*02 (93.9%) -(IGHD) -IGHJ3*01 (93.3%)/HOMO SAPIENS IGHV3-72*01 (81.0%) -(IGHD) -IGHJ6*01 (67.0%)) (8.10.16) (1-125) -HOMO SAPIENS IGHG1*03 G1M3, NG1M1 (CH1 R120 (222) (126-223), HINGE 1-15 (224-238), CH2 L1.3>F (242), L1.2>E (243), D27>A (273) (239-348), CH3 E12 (364), M14(366), F85.1>L (413) (349-453), CHS K2>DEL (454)) (126-454)), (228-214')-DISULFIDE WITH LAMBDA LIGHT CHAIN CHIMERIC (1'-215') (V-LAMBDA (MUS MUSCULUS IGLV1*01 (83.3%) -IGLJ1*01 (100%)/HOMO SAPIENS IGLV8-61*01 (70.8%) - IGLJ3*02 (100%)) (9.3.9) (1'-109') -HOMO SAPIENS IGLC2*01 (100%) (110'-215')); GAMMA1 HEAVY CHAIN HOMO SAPIENS ANTI-MS4A1 (1''-451'') (VH (HOMO SAPIENS IGHV3-9*01 (96.0%) -(IGHD) -IGHJ6*01 (100%)) (8.8.15) (1''-122'') -HOMO SAPIENS IGHG1*03 G1M3, G1M1 (CH1 R120 (219) (123-220), HINGE 1-15 (221-235), CH2 L1.3>F (239), L1.2>E (240), D27>A (270) (236-345), CH3 E12 (361), M14 (363), K88>R (414) (346-450), CHS K2>DEL (451)) (123''-451'')), (225''-214''')-DISULFIDE WITH KAPPA LIGHT CHAIN HOMO SAPIENS (1'''-214''') (V-KAPPA (HOMO SAPIENS IGKV3-11*01 (100%) -IGKJ5*01 (100%)) (6.3.9) (1'''-107''') -HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (153), V101 (191) (108'''-214''')); DIMER (234-231'':237-234'')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO)-S CELL LINE, GLYCOFORM ALFA

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

EPCORITAMAB

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