RINVATERCEPT

UNII:	D674N274QK
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	RINVATERCEPT
GSRS Full Record:	D674N274QK i

2996105-98-5
Activin receptor type 2 (synthetic human extracellular domain 109-amino acid fragment) fusion protein with peptide linker (GGG) fusion protein with immunoglobulin G1 (human γ1-chain Fc region), dimer
Rinvatercept
glycyl (1)-chimeric N-terminal (1-108)-peptide (2-109) combined from the sequences of the extracellular domains of the human activin type 2A and 2B receptors (ACTR-2A/B, ACVR2A/B, activin receptor type IIA/B, ACTR-IIA/B, EC:2.7.11.30), fused via a G3 peptide linker (110-112) to an immunoglobulin G1 (IgG1) Fc fragment (h-CH2-CH3-CHS domains)(113-339) [Homo sapiens IGHG1*01 (hinge (113-122), CH2 (123-232), CH3 (233-337), CHS (338-339))], dimer (118-118':121-121')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells
rinvatercept [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

RINVATERCEPT

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