IXOTATUG

UNII:	D64CJ98P8W
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	IXOTATUG
GSRS Full Record:	D64CJ98P8W i

3018936-99-4
H-gamma1 heavy chain (1-447) [VH Musmus/Homsap (Mus musculus IGHV6-3*01 (88.8%) -(IGHD) -IGHJ2*01 (90.9%) T123>L (112)/Homo sapiens IGHV3-23*03 (82.7%) -(IGHD) -IGHJ5*01 (91.7%) V124>L (113), CDR-IMGT [8.10.8] (26-33.51-60.99-106)) (1-117) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (214) (118-215), hinge 1-15 (216-230), CH2 (231-340), CH3 D12 (356), L14 (358) (341-445), CHS (446-447)) (118-447)], (220-214')-disulfide with L-kappa light chain (1'-214') [V-KAPPA Musmus/Homsap (Mus musculus IGKV12-44*01 (83.2%) -IGKJ1*01 (91.7%) G120>Q (100')/Homo sapiens IGKV1-39*01 (83.2%) -IGKJ2*02 (100%), CDRIMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (226-226'':229-229'')-bisdisulfide, produced in a cell line from Chinese hamster ovary (CHO) cells, derived from the cell line CHO-S, glycoform alfa
IXOTATUG [USAN]
Immunoglobulin G1, anti-(human claudin 6) (human monoclonal TORL-1-23 γ1-chain), disulfide with human monoclonal TORL-1-23 κ-chain, dimer
Immunoglobulin G1-kappa, anti-[Homo sapiens CLDN6 (claudin 6, claudin-6)], monoclonal antibody; H-gamma1 heavy chain (1-447) [VH Musmus/Homsap (Mus musculus IGHV6-3*01 (88.8%) -(IGHD) -IGHJ2*01 (90.9%) T123>L (112)/Homo sapiens IGHV3-23*03 (82.7%) -(IGHD) -IGHJ5*01 (91.7%) V124>L (113), CDRIMGT [8.10.8] (26-33.51-60.99-106)) (1-117) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (214) (118-215), hinge 1-15 (216-230), CH2 (231-340), CH3 D12 (356), L14 (358) (341-445), CHS (446-447)) (118-447)], (220-214')-disulfide with L-kappa light chain (1'-214') [V-KAPPA Musmus/Homsap (Mus musculus IGKV12-44*01 (83.2%) -IGKJ1*01 (91.7%) G120>Q (100')/Homo sapiens IGKV1-39*01 (83.2%) -IGKJ2*02 (100%), CDRIMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (226-226'':229-229'')-bisdisulfide, produced in a cell line from Chinese hamster ovary (CHO) cells, derived from the cell line CHO-S, glycoform alfa
Ixotatug
TORL-1-23 MAB
TORL-1-23 PARENT
immunoglobulin G1-kappa, anti-[Homo sapiens CLDN6 (claudin 6, claudin-6)], monoclonal antibody (ixotatug)
ixotatug [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

IXOTATUG

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