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ABIPAPOGENE SUVAPLASMID

UNII:D3XX2X6TBJ
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:ABIPAPOGENE SUVAPLASMID
GSRS Full Record:

  • 2939766-18-2
  • Abipapogene Suvaplasmid
  • DNA (recombinant mammalian expression vector VB10.16 human cytomegalovirus promoter plus human C-C motif chemokine 3-like 1 protein precursor fusion protein with human immunoglobulin G3 dimerization domain fusion protein with human papillomavirus 16 mutation-inactivated E7/E6 fusion protein gene plus rabbit β-globin polyadenylation signal-specifying)
  • DNA plasmid encoding a mutation-inactivated human papillomavirus type 16 E6 / E7 fusion protein linked to the human cytokine CCL3L1 (chemokine (C-C motif) ligand 3-like 1) via a dimerization module consisting of upper and lower hinge regions and constant heavy chain domain from human immunoglobulin G3 (IgG3). Expression of the transgene is under control of a cytomegalovirus (CMV) promoter/enhancer and terminated by a rabbit β-globin polyadenylation signal. The plasmid also contains a kanamycin resistance gene, an immunostimulatory (CpG-rich) sequence and a pUC origin of replication
  • VB-10.16
  • VB10.16
  • abipapogene suvaplasmid [INN]



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