LIXARKITUG

UNII:	D2WV4EJ95L
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	LIXARKITUG
GSRS Full Record:	D2WV4EJ95L i

3035710-69-8
H-gamma1 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV3-23*01 (92.9%) -(IGHD) -IGHJ6*01 (100%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*03 (100%) G1m3, nG1m1 CH1 R120, CH3 E12, M14 (CH1 R120 (216) (120-217), hinge 1-15 (218-232), CH2 (233-342), CH3 E12 (358), M14 (360) (343-447), CHS (448-449)) (120-449)], (222-219')-disulfide with L-kappa light chain Homo sapiens (1'-219') [V-KAPPA (Homo sapiens IGKV2-28*01 (98.0%) -IGKJ2*01 (100%), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (158'), V101 (196')) (113'-219')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-S, glycoform alfa
INT-020
INT020
Immunoglobulin G1, anti-(human interleukin 3 receptor α-chain) (human monoclonal INT-020 γ1-chain), disulfide with human monoclonal INT-020 κ-chain, dimer
Lixarkitug
immunoglobulin G1-kappa, anti-[Homo sapiens IL3RA (interleukin 3 receptor subunit alpha, interleukin 3 receptor alpha (low affinity), CD123)], Homo sapiens monoclonal antibody (lixarkitug)
lixarkitug [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

LIXARKITUG

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