GLANKIBART

UNII:	CZ9BTC4V32
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	GLANKIBART
GSRS Full Record:	CZ9BTC4V32 i

3081401-47-7
Glankibart
H-gamma4 heavy chain humanized (1-447) [VH (Homo sapiens IGHV4-31*02 (89.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.7.14] (26-33.51-57.96-109)) (1-120) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, 12-G4v5 h P10 (CH1 (121-218), hinge 1-12 S10>P (228) (219-230), CH2 L92 (309) (231-340), CH3 (341-445), CHS (446-447)) (121-447)],(134-213')-disulfide with L-kappa light chain humanized (1'-213') [V-KAPPA (Homo sapiens IGKV1-39*01 (81.1%) -IGKJ2*01 (100%), CDR-IMGT [5.3.9] (27'-31'.49'-51'.88'-96')) (1'-106') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (152'), V101 (190')) (107'-213')]; dimer (226-226'':229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Immunoglobulin G4 [228-proline], anti-(human interleukin 1 receptor-like 2 protein) (human-Mus musculus monoclonal TQS1914 γ4-chain), disulfide with human-Mus musculus monoclonal TQS1914 κ-chain, dimer
glankibart [INN]
immunoglobulin G4-kappa, anti-[Homo sapiens IL1RL2 (interleukin 1 receptor like 2, IL1 receptor-related protein 2, IL1Rrp2, IL1RRP2, IL-36 receptor, IL-36R))], humanized monoclonal antibody (glankibart)

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

GLANKIBART

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