ECAGITATUG

UNII:	CY3YG3C3KT
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ECAGITATUG
GSRS Full Record:	CY3YG3C3KT i

3076369-09-7
Ecagitatug
H-gamma2 heavy chain (1-446) [VH (Homo sapiens IGHV3-30-5*03 (82.7%) -(IGHD) -IGHJ4*01 (92.3%) L123>T (115), CDR-IMGT [8.7.14] (26-33.51-57.96-109)) (1-120) -Homo sapiens IGHG2*01 (100%) G2m.. CH2 V45.1 (CH1 (121-218), hinge 1-12 (219-230), CH2 V45.1 (281) (231-339), CH3 (340-444), CHS (445-446)) (121-446)], (134-218')-disulfide with Lkappa light chain (1'-218') [V-KAPPA Musmus/Homsap (Mus musculus IGKV3-12*01 (81.8%) -IGKJ1*02 (90.9%) G120>Q (104')/Homo sapiens IGKV4-1*01 (79.2%) -IGKJ2*01 (100%), CDR-IMGT [10.3.9] (27'-36'.54'-56'.93'-101')) (1'-111') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (157'), V101 (195')) (112'-218')]; dimer (222-222'':223-223'':226-226'':229-229'')-tetrakisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHOK1SV, lacking the glutamine synthetase (GS-KO) gene, glycoform alfa
Immunoglobulin G2, anti-(Human hepatocyte growth factor receptor c-Met) (human-Mus musculus monoclonal SHR-1826 γ2-chain), disulfide with human-Mus musculus monoclonal SHR-1826 κ-chain, dimer
SHR-1826 mAb
SHR1826 mAb
ecagitatug [INN]
immunoglobulin G2-kappa, anti-[Homo sapiens MET (met proto-oncogene, hepatocyte growth factor (HGF) receptor, HGFR, scatter factor (SF) receptor, HGF/SF receptor, receptor tyrosine-protein kinase c-met, papillary renal cell carcinoma 2, RCCP2)], monoclonal antibody (ecagitatug)

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ECAGITATUG

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