TEPILUKIMIG

UNII:	C4X2B2V5B3
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	TEPILUKIMIG
GSRS Full Record:	C4X2B2V5B3 i

2985643-31-8
Immunoglobulin G1 [238-phenylalanine,239-glutamic acid,335-serine,358-cysteine,370-tryptophan], bispecific, anti-(human thymic stromal lymphopoietin) (human monoclonal GR2002 γ1-chain), (230→225′),(233→228′),(358→348′)-tris(disulfide) with immunoglobulin G1 [136′-glutamic acid,202′-aspartic acid,213′-threonine,233′-phenylalanine,234′-glutamic acid,267′-glutamine,273′-glutamine,330′-serine,348′-cysteine,354′-glutamine,365′-serine,367′-alanine,406′-valine,418′-glutamic acid] anti-(human thymic stromal lymphopoietin) (human monoclonal GR2002 γ1-chain), disulfide with human monoclonal GR2002 κ-chain
Tepilukimig
immunoglobulin (H-gamma1_L-kappa)_(H-gamma1_L-kappa), anti-[Homo sapiens TSLP (thymic stromal lymphopoietin) IL7R (interleukin 7 receptor, IL7RA, CD127) binding site epitope] and anti-[Homo sapiens TSLP (thymic stromal lymphopoietin) CRLF2 (cytokine receptor like factor 2, TSLPR, thymic stromal lymphopoietin receptor) binding site epitope], humanized monoclonal antibody, biparatopic, bivalent
immunoglobulin (H-gamma1_L-kappa)_(H-gamma1_L-kappa), anti-[Homo sapiens TSLP (thymic stromal lymphopoietin) IL7R (interleukin 7 receptor, IL7RA, CD127) binding site epitope] and anti-[Homo sapiens TSLP (thymic stromal lymphopoietin) CRLF2 (cytokine receptor like factor 2, TSLPR, thymic stromal lymphopoietin receptor) binding site epitope], humanized monoclonal antibody, biparatopic, bivalent (tepilukimig)
tepilukimig [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

TEPILUKIMIG

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