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BREZOSIRAN

UNII:BY4G2GL2SQ
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:BREZOSIRAN
GSRS Full Record:
BY4G2GL2SQ
i

  • 3059403-91-4
  • Brezosiran
  • RNA, ((5′,6′-dideoxy-6′-phosphono-β-D-ribo-hex-5-enofurano)Um-sp-(2′-deoxy-2′-fluoro)A-sp-Um-Cm-dA-Gm-C-(2′→5′)-Um-Um-Um-Um-dC-Cm-(2′-deoxy-2′-fluoro)A-Gm-dG-Gm-Um-Cm-Gm-Cm-sp-Cm-sp-Gm), complex with RNA (Gm-sp-Cm-sp-Gm-Am-Cm-(2′-O-hexadecyl)C-(2′-deoxy-2′-fluoro)C-Um-(2′-deoxy-2′-fluoro)G-(2′-deoxy-2′-fluoro)G-(2′-deoxy-2′-fluoro)A-Am-Am-Am-Gm-Cm-Um-Gm-Am-sp-Um-sp-Am) (1:1)
  • all-P-ambo-2'-O-methyl-P-thioguanylyl-(3'→5')-2'-O-methyl-P-thiocytidylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-hexadecylcytidylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methyl-P-thioadenylyl-(3'→5')-2'-O-methyl-P-thiouridylyl-(3'→5')-2'-O-methyladenosine, duplex with all-P-ambo-2'-O-methyl-P-thioguanylyl-(5'→3')-2'-O-methyl-P-thiocytidylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-deoxyguanylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-deoxycytidylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methyluridylyl-(5'→2')-cytidylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-deoxyadenylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-O-methyl-P-thiouridylyl-(5'→3')-2'-deoxy-2'-fluoro-P-thioadenylyl-(5'→3')-(5'E)-2'-O-methyl-5',C 5' -didehydro-O5' -carba-5'-uridylic acid
  • brezosiran [INN]




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