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RALUDOTATUG DERUXTECAN

UNII:BPQ010OFD7
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:RALUDOTATUG DERUXTECAN
GSRS Full Record:
BPQ010OFD7
i

  • 2610074-57-0
  • DS-6000A
  • DS6000A
  • Immunoglobulin G1, anti-(human G cadherin 6) (human-Rattus norvegicus monoclonal MABU-9014a γ1-chain), complex with human-Rattus norvegicus monoclonal MABU-9014a κ-chain, dimer, octakis(thioether) with N-[6-(3-mercapto-2,5-dioxo-1-pyrrolidinyl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[[2-[[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-1-yl]amino]-2-oxoethoxy]methyl]glycinamide
  • RALUDOTATUG DERUXETCAN [USAN]
  • Raludotatug Deruxtecan
  • Raludotatug deruxtecan [WHO-DD]
  • gamma1 heavy chain humanized (1-452) [VH (Homo sapiens IGHV1-3*01 (86.7%)-(IGHD)-IGHJ4*01(93.3%), CDR-IMGT [8.8.15] (26-33.51-58.97-111))(1-122) -Homo sapiens IGHG1*03, G1m3, nG1m1 (CH1 R120 (219)(123-220), hinge 1-15 (221-235), CH2 (236-345), CH3 E12 (361), M14 (363) (346-450), CHS (451-452)) (123-452)], (225-213')-disulfide with kappa light chain humanized (1'-213') [V-KAPPA (Homo sapiens IGKV1-39*01 (86%) -IGKJ1*01 (91.7%), CDR-IMGT[6.3.8] (27-32.50-52.89-96)) (1'-106')-Homo sapiens IGKC*01 (100%), Km3 A45.1 (152), V101(190) (107'-213')]; dimer (231-231'': 234-234'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa; conjugated, on an average of 8 cysteinyl, to deruxtecan, comprising a linker and a camptothecin derivative
  • immunoglobulin G1-kappa, anti-[Homo sapiens CDH6(cadherin 6, K-cadherin (foetal kidney), cadherin 6 type 2)], humanized monoclonal antibody conjugated to deruxtecan, comprising a linker and a camptothecin derivative
  • raludotatug deruxtecan [INN]




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