ZELDESMERAN

UNII:	BD2KE88JH4
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ZELDESMERAN
GSRS Full Record:	BD2KE88JH4 i

2726459-47-6
RNA (recombinant 5′-(m7G-(5′→5′)-ppp-Gm)-capped all uridine→N1-methylpseudouridine-substituted severe acute respiratory syndrome coronavirus 2 spike glycoprotein [614-glycine]-specifying plus 5′- and 3′-untranslated flanking region-containing poly(A)-tailed messenger PTX-COVID19-B), inner salt
Zeldesmeran
messenger RNA (mRNA), 5'-capped, encoding a full-length, codon-optimised version of the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) spike (S) glycoprotein (based upon GenBank ID: MT270101.1), containing the D614G mutation, flanked by a 5' untranslated region (5'UTR) derived from the 5'UTR of tobacco etch virus and a 3' untranslated region (3'UTR) derived from the 3'UTR of Xenopus laevis beta globin mRNA, and terminated with a 3' polyadenylation (polyA) tail; contains N<sup>1</sup>-methylpseudouridine instead of uridine (all-U>m1Ψ)
zeldesmeran [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ZELDESMERAN

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