TROVOSTOBART

UNII:	ATY7DC4MSF
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	TROVOSTOBART
GSRS Full Record:	ATY7DC4MSF i

3006784-09-1
H-gamma1 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV4-59*01 (99.0%) -(IGHD) -IGHJ3*02 (93.3%) T125>I (114), CDR-IMGT [8.7.11] (26-33.51-57.96-106)) (1-117) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, 9-G1v21 CH2 Y15.1, T16, E18 (CH1 K120 (214) (118-215), hinge 1-15 (216-230), CH2 M15.1>Y (252), S16>T (254), T18>E (256) (231-340), CH3 D12 (356), L14 (358) (341-445), CHS (446-447)) (118-447)], (220-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV3-11*01 (96.8%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (CKAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (226-226'':229-229'')-bisdisulfide, produced in a cell line derived from Chinese hamster ovary (CHO) cells, glycoform alfa
Immunoglobulin G1 [252-tyrosine,254-threonine,256-glutamic acid], anti-(human v-domain immunoglobulin suppressor of T-cell activation) (human monoclonal KVA12123 γ1-chain), disulfide with human monoclonal KVA12123 κ-chain, dimer
KVA-12123
KVA12123
Trovostobart
immunoglobulin G1-kappa, anti-[Homo sapiens VSIR (V-set immunoregulatory receptor, B7H5, B7-H5, PDCD1 homolog, PD-1H, stress induced secreted protein 1, SISP1, V-domain Ig suppressor of T cell activation, VISTA)], Homo sapiens monoclonal antibody (trovostobart)
trovostobart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

TROVOSTOBART

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