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UFRENMERAN

UNII:AP7FFK83RM
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:UFRENMERAN
GSRS Full Record:

  • 2749556-96-3
  • RNA (recombinant 5′-(m7G-(5′→5′)-ppp-Am)-capped all cytidine→5-methylcytidine, all uridine→5-methyluridine human β-globin 5′-untranslated region plus severe acute respiratory syndrome coronavirus 2 strain Wuhan-Hu-1 (1-13)-(319-541)-spike glycoprotein precursor-specifying plus human β-globin 3′-untranslated region poly(A)-tailed messenger DS08035531), inner salt
  • Ufrenmeran
  • Ufrenmeran [WHO-DD]
  • messenger RNA (mRNA), 5'-capped, encoding the codon-optimized receptor binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, Wuhan-Hu-1 isolate, GenBank: MN908947.3) spike (S) glycoprotein, expressed as a fusion protein with the S glycoprotein signal peptide, flanked by 5' and 3' untranslated regions (UTRs) derived from the human β-globin gene (GenBank ID: NM_000518.5) and a 3' polyadenylation (polyA) tail; contains 5-methyluridine instead of uridine (all-U>5-Me-U) and 5-methylcytidine instead of cytidine (all-C>5-Me-C)
  • ufrenmeran [INN]



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