ZILTIVEKIMAB

UNII:	AN3Y2B4SX4
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ZILTIVEKIMAB
GSRS Full Record:	AN3Y2B4SX4 i

2226654-05-1
COR-001
COR001
Immunoglobulin G1 [255-tyrosine,257-threonine,259-glutamic acid], anti-(human interleukin 6) (human monoclonal 2E2.3A9.6A3 γ1-chain), disulfide with human monoclonal 2E2.3A9.6A3 κ-chain, dimer
MEDI 5117 [WHO-DD]
MEDI-5117
MEDI5117
NN-6018
NN6018
WBP-216
WBP216
ZILTIVEKIMAB [USAN]
Ziltivekimab
Ziltivekimab [WHO-DD]
immunoglobulin G1-kappa, anti-[Homo sapiens IL6 (interleukin 6, IL-6)], monoclonal antibody; gamma1 heavy chain humanized (1-450) [VH (Homo sapiens IGHV3-66*01 (88.8%) -(IGHD) -IGHJ1*01 (90.9%)) [8.8.13] (1-120) -Homo sapiens IGHG1*03 G1m3, nG1m1 (CH1 R120 (217) (121-218), hinge 1-15 (219-233), CH2 M15.1>Y (255), S16>T (257), T18>E (259) (234-343), CH3 E12 (359), M14 (361) (344-448), CHS (449-450)) (121-450)], (223-213')-disulfide with kappa light chain Homo sapiens (1'-213') [V-KAPPA (Homo sapiens IGKV1-5*03 (96.7%) -IGKJ2*03 (100%)) [6.3.8] (1'-106') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (152), V101 (190) (107'-213')]; dimer (229-229'':232-232'')-bisdisulfide, produced in Chinese Hamster Ovary (CHO)-GS cell line, glycoform alfa
ziltivekimab [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ZILTIVEKIMAB

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