VONAPRUMENT

UNII:	9HLL22LOX6
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	VONAPRUMENT
GSRS Full Record:	9HLL22LOX6 i

3050549-24-8
ANX-007
ANX007
Immunoglobulin Fab-G1kappa (VH-CH1_L-kappa), anti-[Homo sapiens C1q], humanized monoclonal antibody fragment; Fab-G1 VH-CH1 chain (1-229) [VH Musmus/Homsap (Mus musculus IGHV1-64*01 (82.5%) -(IGHD) -IGHJ4*01 (92.9%) S123>T (116)/Homo sapiens IGHV1-46*01 (79.4%) -(IGHD)-IGHJ6*01 (92.9%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG1*01 CH1-h (100%), G1m17 CH1 K120 (CH1 K120 (218) (122-219), hinge 1-10 (220-229)) (122-229)], (224-214')-disulfide with L-kappa light chain (1'-214') [V-KAPPA (Homo sapiens IGKV1-9*03 (80.9%) -IGKJ2*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (153), V101 (191) (108'-214')], produced in Chinese hamster ovary (CHO) cells, cell line CHO, non-glycosylated
Immunoglobulin IgG1 Fab fragment, anti-(human complement C1q) (human-Mus musculus monoclonal ANX007 γ1-chain), disulfide with human-Mus musculus monoclonal ANX007 κ-chain
VH-G1(CH1-10h) chain anti-C1q (H) (1-229) [VH Musmus/Homsap (Mus musculus IGHV1-64*01 (82.5%) -(IGHD) -IGHJ4*01 (92.9%) S123>T (116)/Homo sapiens IGHV1-46*01 (79.4%) -(IGHD) -IGHJ6*01 (92.9%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -G1(CH1-10h) Homo sapiens IGHG1*01 CH1 G1m17 K120 (CH1 K120 (218) (122-219), hinge 1-10 (220-229)) (122-229)], (224-214')-disulfide with L-kappa light chain anti-C1q (L') (1'-214') [V-KAPPA Musmus/Homsap (Mus musculus IGKV16-104*01 (89.5%) -IGKJ2*03 (90.9%) S120>Q (100')/Homo sapiens IGKV1-9*03 (80.9%) -IGKJ2*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')], produced in Chinese hamster ovary (CHO) cells, non-glycosylated
VONAPRUMENT [USAN]
Vonaprument
immunoglobulin Fab VH-G1(CH1-10h)_L-kappa, anti-[Homo sapiens C1q (complement C1q) globular head region], monoclonal antibody (vonaprument)
vonaprument [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

VONAPRUMENT

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