GIRANCITUG

UNII:	9AB5PRA7TP
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	GIRANCITUG
GSRS Full Record:	9AB5PRA7TP i

3024821-77-7
Girancitug
H-gamma1 heavy chain Homo sapiens (1-446) [VH (Homo sapiens IGHV3-21*01 (99.0%) -(IGHD) -IGHJ6*01 (100%), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (213) (117-214), hinge 1-15 (215-229), CH2 (230-339), CH3 D12 (355), L14 (357) (340-444), CHS (445-446)) (117-446)], (219-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-33*01 (93.7%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO)/dhFr- cell line lacking the enzyme dihydrofolate reductase (DHFR), glycoform alfa
Immunoglobulin G1, anti-(human vascular endothelial growth factor receptor 2) (human monoclonal BC001 γ1-chain), disulfide with human monoclonal BC001 κ-chain, dimer
girancitug [INN]
immunoglobulin G1-kappa, anti-[Homo sapiens KDR (kinase insert domain receptor, vascular endothelial growth factor receptor 2, VEGFR2, VEGF-R2, FLK1, CD309)], Homo sapiens monoclonal antibody (girancitug)

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

GIRANCITUG

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