VILASTOBART

UNII:	8FUE2D4G82
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	VILASTOBART
GSRS Full Record:	8FUE2D4G82 i

2760549-50-4
CTLA4 (cytotoxic T-lymphocyte associated protein 4, CTLA-4, CD152)], humanized monoclonal antibody; gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV1-69*08 (84.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, D12, L14, G1v7 CH2 D3, E117 (CH1 K120 (216) (120-217), hinge 1-15 (218-232), CH2 S3>D (241), I117>E (334) (233-342), CH3 D12 (358), L14 (360) (343-447), CHS (448-449)) (120-449)], (222-241')-disulfide with fused prodomain kappa light chain humanized (1'-241') [prodomain (1'-28') fused to V- KAPPA (Homo sapiens IGKV6-21*02 (78.5%) -IGKJ4*01 (100%), CDR-IMGT [5.3.9] (55'-59'.77'-79'.116'-124')) (29'-134') -Homo sapiens IGKC*01, Km3 A45.1 (180'), V101 (218') (135'-241')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Immunoglobulin G1 [241-aspartic acid,334-glutamic acid], anti-(human cytotoxic T-lymphocyte-associated protein 4) (human-Rattus norvegicus monoclonal XTX101 γ1-chain), disulfide with prodomain protein (synthetic masking moiety and protease-cleavable moiety) fusion protein with human-Rattus norvegicus monoclonal XTX101 κ-chain, dimer
VILASTOBART [USAN]
Vilastobart
XTX 101 [WHO-DD]
XTX-101
XTX101
gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV1-69*08 (84.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT[8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, D12, L14, G1v7 CH2 D3, E117 (CH1 K120 (216) (120-217), hinge 1-15 (218-232), CH2 S3>D(241), I117>E (334) (233-342), CH3 D12 (358), L14 (360) (343-447), CHS (448-449)) (120-449)], (222-241')-disulfide with fused prodomain kappa light chain humanized (1'-241') [prodomain (1'-28') fused to V- KAPPA (Homo sapiens IGKV6-21*02 (78.5%) -IGKJ4*01 (100%), CDR-IMGT [5.3.9] (55'-59'.77'-79'.116'-124'))(29'-134') -Homo sapiens IGKC*01, Km3 A45.1 (180'), V101(218') (135'-241')]; dimer (228-228'':231-231'')-bisdisulfide
vilastobart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

VILASTOBART

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