GALVOKIMIG

UNII:	85A4592PC8
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	GALVOKIMIG
GSRS Full Record:	85A4592PC8 i

2648456-30-6
Fused G1(VH-CH1-h)-scFv heavy-kappa heavy chain humanized (1-492) [VH-IGHG1 CH1-h anti-IL-17A/F humanized (1-228) [VH (Homo sapiens IGHV3-7*01 (88.7%) -(IGHD) -IGHJ6*01 (90.9%) T123>L (120), CDR-IMGT [8.8.18] (26-33.51-58.97-114)) (1-125)-Homo sapiens IGHG1*01, G1m17 CH1 K120 (CH1 K120 (222) (126-223), hinge 1-5 (224-228)(126-228))] -11-mer (seryl-tetraglycyl-threonyl-tetraglycyl-seryl) linker (229-239) -scFv heavy-kappa anti-ALB humanized, scFv-v1 C49 (VH)-C120 (VL) (240-492) [VH (Homo sapiens IGHV3-23*01 (78.6%) -(IGHD) -IGHJ2*01 (93.3%), C49 (283), CDR-IMGT [8.7.15] (265-272.290-296.335-349)) (240-360) -20-mer tetrakis(tetraglycyl-seryl) linker (361-380) -V-KAPPA (Homo sapiens IGKV1-12*01 (86.5%) -(IGHD) -IGKJ1*01 (90.9%) C120 (483), CDR-IMGT [7.3.11] (407-413.431-433.470-480))(381-492)]], (228-214')-disulfide with the fused L-kappa-scFv heavy-kappa light chain humanized (1'-469') [L-kappa anti-IL-17A/F humanized (1'-215') [V-KAPPA (Homo sapiens IGKV1-13*02 (80.0%) -IGKJ1*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%),Km3, A45.1 (153), V101 (191) (108'-214')] -11-mer seryl-bis(tetraglycyl-seryl) linker (215'-225') -scFv heavy-kappa anti-IL13 humanized, scFv-v1 C49 (VH)-C120 (VL) (226'-469') [VH(Homo sapiens IGHV1-69*08 (81.6%) -(IGHD) -IGHJ1*01 (100%), C49 (269'), CDR-IMGT [8.8.9] (251'-258'.276'-283'.322'-330')) (226'-341') -20-mer tetrakis(tetraglycyl-seryl) linker (342'-361') -V-KAPPA (Homo sapiens IGKV1-NL1*01(83.9%) -(IGHD) -IGKJ2*01 (91.7%), C120 (460'), CDR-IMGT [6.3.8] (388'-393'.411'-413'.450'-457')) (362'-469')]], produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, non-glycosylated
GALVOKIMIG [USAN]
Galvokimig
Immunoglobulin G1(VH-CH1-h)-scFv_L-kappa-scFv, anti-[Homo sapiens IL17A (interleukin 17A, IL-17A) and IL17F (interleukin 17F, IL-17F)], anti-[Homo sapiens IL13 (interleukin 13, IL-13)], anti-[Homo sapiens ALB (albumin, human serum albumin, HSA], humanized monoclonal antibody, trispecific, trivalent
Immunoglobulin G1, anti-(human interleukin 17A/interleukin 17F) (human-Rattus norvegicus γ1-chain C-terminal fragment) fusion protein with peptide linker (SGGGGTGGGGS) fusion protein with immunoglobulin [283-cysteine,483-cysteine] anti-(human serum al...
UCB-9741
UCB9741
galvokimig [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

GALVOKIMIG

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