ONCR-177

UNII:	83P3OQ67ZT
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ONCR-177
GSRS Full Record:	83P3OQ67ZT i

HSV-1 MIR-ATTENUATED ONCOLYTIC ONCR-177
ONCR 177 [WHO-DD]
ONCR-177, AN MIR-ATTENUATED ONCOLYTIC HSV-1 EXPRESSING ARMED WITH FIVE TRANSGENES (THE NK AND T CELL ACTIVATING CYTOKINE IL-12, THE CHEMOKINES CCL4 AND FLT3LG (EXTRACELLULAR DOMAIN) TO ALLOW FOR EXPANSION AND RECRUITMENT OF CLASSICAL DENDRITIC CELLS, AND ANTAGONISTS TO THE CLINICALLY VALIDATED IMMUNE CHECKPOINT TARGETS PD-1 AND CTLA-4)

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UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ONCR-177

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