GORIVITUG

UNII:	83DC7W9PBC
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	GORIVITUG
GSRS Full Record:	83DC7W9PBC i

2765086-18-6
GORIVITUG [USAN]
Gorivitug
Immunoglobulin G1, anti-(severe acute respiratory syndrome coronavirus 2 spike glycoprotein receptor-binding domain) (human monoclonal REGN15160 γ1-chain), disulfide with human monoclonal REGN15160 κ-chain, dimer
REGN-15160
REGN15160
gamma1 heavy chain Homo sapiens (1-453) [VH (Homo sapiens IGHV3-64D*06 (94.9%) -(IGHD) -IGHJ6*01 (100%), CDR-IMGT [8.8.16] (26-33.51-58.97-112)) (1-123)-Homo sapiens IGHG1*01, G1m17,1 (CH1 K120 (220) (124-221), hinge 1-15 (222-236), CH2 (237-346), CH3 D12 (362), L14 (364) (347-451), CHS (452-453)) (124-453)], (226-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01(96.8%) -IGKJ3*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (232-232'':235-235'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
gorivitug [INN]
immunoglobulin G1-kappa, anti-[Homo sapiens severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

GORIVITUG

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